1994 - Specialist degree in Chemistry, Chemical Faculty of Kyiv Taras Shevchenko National University. 1998 – Ph.D degree in chemistry, Chemical Department of Kyiv Taras Shevchenko National University (his scientific adviser is Prof. A.I. Brusilovets). His Ph.D. thesis was focused on the study of interaction of low coordinated phosphorus with metal alkoxides and alkoxyhalogenides. Volodymyr have been working in IMBG since 2001. Now he is a senior research scientist, deputy head of Department of Combinatorial Chemistry (IMBG) and the Head of Molecular Design Group. Volodymyr is a co-author of 17 publications in scientific journals.

E-mail: hive@ukr.net

Education and Academic qualifications :

1982-1984 -4th Kiev medical school (Diploma)
1985-1990 - National Kiev University Biological department (Diploma with honor) majored in Biology, Molecular Biology, teaching of biology and chemistry. Awarded Degree of Master of Sciences
1997 - PhD in molecular biology (Institute of Molecular Biology and Genetics of the National Academy of Sciences of Ukraine).

Scientific experience :

1988 – untill now - Institute of Molecular Biology and Genetics of the National Academy of Sciences of Ukraine (IMBiG).
2005-untill now - Department of combinatorial chemistry, IMBiG
Position : Senior Researcher , Group leader
Project: Search of small molecule synthetic inhibitors of human protein kinases ( in vitro kinase assays, screening of combinatorial libraries).
2001-2005 - Department of molecular mechanisms of cell growth
Position : Senior Investigator
Project: Identification and functional characterization of novel PTEN binding partners using Yeast Two Hybrid approach
1998-2001 - Laboratory of cell growth regulation
Position: Researcher Scientist
Projects: Characterization of p70 S6 kinase binding partners; Regulation of p70 S6 kinase alpha and beta isoforms in normal and cancer cells.
1990-1998 - Department of molecular virology
Status: Junior Researcher, PhD student
Research work for seeking scientific degree of Ph.D. in molecular biology Ph.D. In 1997 – completed the Thesis “Constructing of eukaryotic vector expressing antisense RNA against Human Immunodeficiency Virus Type 1”
1988-1990 - Department of Nucleic Acids Structure and Function ,
Status: Technician associate,
Researcher assistant, student position.

Trainings & awards

1996 “Ukrainian Ministry of Sciences Award for Ph.D. students and Young Scientists “
1998 “Welcome Trust”, Post-Doctoral Travel Grant. Ludwig Institute for Cancer Research, UCL, UK
2001 “Royal Society” Fellowship, Ludwig Institute for Cancer Research, London Branch
2006 Applied Biosystems training center, Warrington, 2005 Training on basics technique and instrument manegement for ABI 3130 DNA analizer .

Professional Skills

• In vitro kinase assay: Biochemical Tests of kinase activity by different methods (p32-gamma ATP assay; Luciferase method (ATP-consumption) ELISA method with anti-phospho-specific MAbs
• Eukaryotic cell culture, transfection by recombinant DNA;
• DNA cloning; DNA sequencing by Sanger method, automated sequencing (ABI 3130);
  Molecular diagnostics: hybridization, Southern and Northern blot; PCR methods (Real time PCR)
• Expression and isolation of recombinant proteins in E coli
  Yeast-two-hybrid system
• Spectroscopic and fluoroscopic studding of nucleic acids with molecular dyes and probes
  

E-mail: kukharenko@gmail.com

  Andriy studied at the Biological Department of Kyiv Taras Shevchenko National University. In 2000 he received B. S. Degree, in 2001 - Specialist degree in Biology (specialization in Molecular Biology and Biochemistry). Since 2001 Andriy have been working in Molecular Design Group of Department of Combinatorial Chemistry (Institute of Molecular Biology and Genetics, NAS of Ukraine). In 2007 he obtained PhD degree under supervising of Dr. Sci., Prof. Sergiy Yarmoluk. The title of Andriy’s PhD thesis is: “In Silico Design of Protein Kinase CK2 inhibitors”. Andriy is a co-author of 15 scientific papers.

E-mail: andrew_golub@ukr.net

    Alexander is a PhD student at the Biological Department of Kyiv Taras Shevchenko National University (Kyiv, Ukraine). In 2004 he obtain a distinction diploma of Master of Science in Biotechnology. From 2001 Alexander works in Molecular Design Group of Department of Combinatorial Chemistry of IMBG. In 2008 he has obtained PhD degree in Biology (speciality: Biotechnology). His thesis is related to development of technology of organic molecules to biomolecular targets affinity estimation in field of high-throughput receptor-based in silico screening. Alexander is a co-author of 10 papers published in scientific journals. He is an author of several molecular modeling software programs.

E-mail: yakovenko_a@ukr.net

    Galyna is a student at the Biological Department of Kyiv Taras Shevchenko National University (specialization in Biotechnology). In 2007 she received B. S. Degree in Biology. Galyna is a co-author of two scientific papers.

E-mail: volinetc_galina@mail.ru

    In 2007 Olga received the diploma of the master in biotechnology at department of Biotechnology and Biotechnics of National Technical University of Ukraine "The Kiev Polytechnical Institute" (specialization "industrial biotechnology"). Currently Olga is postgraduate student of IMBG NAS of Ukraine (specialization - molecular biology). Olga's scientific interests are related to development of small-molecule inhibitors of human protein kinase ASK1.

E-mail: sovetova@bigmir.net

Andriy was studied at Biological Department of Kyiv Taras Shevchenko National University and in 2007 he was obtained diploma of master in biochemistry. Since 2007 Andriy has been working at Molecular Design Group of Department of Combinatorial Chemistry (Institute of Molecular Biology and Genetics, NAS of Ukraine).

E-mail: andrey.grisch@gmail.com